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  Cost Effectiveness of Pharmacotherapy for the Prevention of Migraine -- CNS Drugs

Yu J et al. – To compare the cost effectiveness of adding preventive treatment to abortive therapy for acute migraine with abortive therapy for acute migraine alone in the primary care setting...Preventive medications appear to be a cost–effective approach to the management of migraine in the primary care setting compared with the approach of abortive treatment only. Among those preventive agents, probabilistic sensitivity analysis suggests that, when the societal willingness–to–pay (WTP) is <$US18000 per quality–adjusted life–years (QALYs) gained, amitriptyline 75mg/day is most likely to be considered a cost–effective option.

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