Suthisisang CC et al. – The available evidence suggests that naproxen sodium is more effective but may cause more adverse events than placebo in the acute treatment of moderate to severe migraine. It is effective in reducing headache intensity, rendering pain–free at 2 hours and improving migraine–associated symptoms. However, its effectiveness relative to other active comparators needs to be better defined by appropriate head–to–head clinical trials. ... Click Here to Read More Click Here to Read More