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Summary of von Willebrand disease

  • Von Willebrand disease is the most common inherited bleeding disorder.

  • People with von Willebrand disease may have low levels of or a defective clotting protein in their blood. This clotting protein is called von Willebrand factor.

  • Low levels of clotting factors or factors that do not work correctly can slow the process to stop bleeding after an injury.

  • Von Willebrand disease is an inherited disorder. This means that it is passed down from parent to child.

  • Von Willebrand disease affects men and women equally.

  • The signs and symptoms of von Willebrand disease depend on the type you have. Most cases of von Willebrand disease are mild.

  • Blood tests are used to diagnose von Willebrand disease. These tests check how long it takes for your blood to clot, your level of von Willebrand factor, and how well the von Willebrand factor in your blood is working.

  • There are three types of von Willebrand disease:

    • Type I is the most common and mildest form of the disease
    • Type II is usually a mild-to-moderate form of the disease
    • Type III is very rare and is the most severe form of the disease.

  • Doctors use medicines and factor replacement therapy to treat the disease.

  • Once the type of von Willebrand disease is diagnosed, your doctor will determine what treatment you will need. The severity of your symptoms will also determine what treatment is best for you.

  • It is important to follow your treatment plan and see your doctor regularly. Contact your doctor if you have any questions or concerns.

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Source: NHLBI


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