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Ulcerative Colitis

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Research

Therapies that are being tested for usefulness in treating the disease include

  • Biologic agents. These include monoclonal antibodies, interferons, and other molecules made by living organisms. Researchers modify these drugs to act specifically but with decreased side effects, and are studying their effects in people with ulcerative colitis.

  • Budesonide. This corticosteroid may be nearly as effective as prednisone in treating mild ulcerative colitis, and it has fewer side effects.

  • Heparin. Researchers are examining whether the anticoagulant heparin can help control colitis.

  • Nicotine. In an early study, symptoms improved in some patients who were given nicotine through a patch or an enema. (This use of nicotine is still experimental--the findings do not mean that people should go out and buy nicotine patches or start smoking.)

  • Omega-3 fatty acids. These compounds, naturally found in fish oils, may benefit people with ulcerative colitis by interfering with the inflammatory process.

 
Source: National Institutes of Health




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